Since Sami was a kid when Adrienne was first on I don’t think they had much to do with each other until recently but I do know Adrienne had a problem in the beginning with Sonny and Will getting together and she was very vocal. I think she even made a comment that Will would hurt her son because of having Sami for a mother. Adrienne of course was basing her opinion on how messed up Sami is and how she goes from man to man and breaks each one’s heart. This of course sent Sami into protective mama mode.
Not sure if this is the true reason or not.